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Lymphatic metastasis is related to the epithelial-mesenchymal transition and expressions of VEGF, MMP-9, and COX-2 in breast cancer

Lihui WANG, Lianhong LI, Shen LV, Shujun FAN, Li ZHAN, Bo WANG, Zhong ZHANG

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 164-170 doi: 10.1007/s11684-009-0038-1

Abstract: expressions of N-Cad, VEGF, MMP-9, and COX-2 in cases with lymph node metastasis were significantly higher) was 78.3%, while that without EMT (higher E-Cad expression and lower N-Cad expression) was 11.1%.In the cases with higher grade, the expression of E-Cad was decreased, while that of N-Cad was increasedHigher microvascular density (MVD) was also found to be significantly associated with lymphatic metastasis( <0.05), and the cases with higher MVD had shorter survival time.

Keywords： epithelial-mesenchymal transition     vascular endothelial cell growth factor     matrix metalloproteinase-9     cyclooxygenase-2     highermicrovascular density     breast cancer    

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FUNCTIONAL GAIN OF FRUIT NETTED-CRACKING IN AN INTROGRESSION LINE OF TOMATO WITH HIGHER EXPRESSION OF

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 2,

Abstract:

Fruit cracking is a major disorder that affects the integrity of fruit and reduces the commercial value of tomato and other fleshy fruit. Here, we have found a novel fruit ‘netted-cracking’ (FNC) phenotype in tomato introgression line IL4-4 which is present in neither the donor parent (LA0716) nor the receptor parent (M82). An F2 population was generated by crossing IL4-4 with M82 to genetically characterize the FNC gene and this showed that a single dominant gene determined fruit netted-cracking. Further map-based cloning narrowed down the FNC locus to a 230 kb region on chromosome 4. Sequencing and annotation analysis show that FNC(Solyc04 g082540) was the most likely candidate gene. Functional characterization of FNC by overexpressing FNCAC and FNCIL4-4resulted in the fruit netted-cracking phenotype, suggesting that the FNC transcript level results in the functional gain of fruit netted-cracking. These findings were further confirmed by FNC ortholog in netted-cracking pepper and melon, indicating a common regulatory mechanism in different plant species. Furthermore, cytoplasm and nucleus-localized FNC indicates increased expression of genes involved in suberin, lignin, lipid transport and cell wall metabolism. These findings provide novel genetic insights into fruit netted-cracking and offer a way to promote molecular improvement toward cracking resistant cultivars.

 

Keywords： fine mapping / fruit netted-cracking / introgression line / transcript level    

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Higher-order mode effects on the seismic performance of tall piers

Zhongguo GUAN, Jianzhong LI, Yan XU, Hao LU

Frontiers of Structural and Civil Engineering 2011, Volume 5, Issue 4,   Pages 496-502 doi: 10.1007/s11709-011-0131-9

Abstract: The effect of higher-order modes was studied specifically.The results showed that higher-order modes significantly contributed to the structural seismic responseHigher-order modes also led to an out-of-phase response between the hinge rotation at the pier bottom

Keywords： tall bridges     higher-order mode effects     incremental dynamic analysis    

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Theoretical Study of Color Gamut of Higher Plant Leaves

Cheng Xiaofang,Dong Jinyi,Fan Xueliang,Ding Jinlei

Strategic Study of CAE 2006, Volume 8, Issue 12,   Pages 66-69

Abstract:

The chlorophylls and cartotenoids are the main pigments in leaves of the higher plants, which giveingclassical absorption spectrum and the law of additive color mixing, the theoretical color gamut of higher

Keywords： higher plant     pigment     absorption spectra     chromaticity coordinate     color gamut    

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Higher Moment Method in Reliability Analysis of Engineering Structure

Gong Fengqiang,Li Xibing,Deng Jian

Strategic Study of CAE 2006, Volume 8, Issue 5,   Pages 69-73

Abstract:

A higher moment method with the basis of Chebyshev polynomial { Tk(x)} is presented, whichThe equations of optimal probability density function of stochastic variable or limit state functionare derived by use of the higher moments of the function.

Keywords： structure reliability     higher moment     Chebyshev polynomial     failure probability    

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Higher heating value prediction of torrefaction char produced from non-woody biomass

Nitipong SOPONPONGPIPAT,Dussadeeporn SITTIKUL,Unchana SAE-UENG

Frontiers in Energy 2015, Volume 9, Issue 4,   Pages 461-471 doi: 10.1007/s11708-015-0377-3

Abstract: The higher heating value of five types of non-woody biomass and their torrefaction char was predictedproximate analysis data, the mass fraction of fixed carbon and volatile matter had a strong effect on the higherelemental analysis data, the mass fraction of carbon, hydrogen, and oxygen had a strong effect on the higherheating value, while no relationship between the higher heating value and mass fractions of nitrogen

Keywords： higher heating value     correlation     biomass     proximate analysis     ultimate analysis    

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Effectiveness of quality of care for patients with type 2 diabetes in China: findings from the Shanghai Integration Model (SIM)

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 126-138 doi: 10.1007/s11684-021-0897-7

Abstract: Patients who achieved the target levels for blood pressure (BP)<130/80 mmHg and low-density lipoprotein-cholesterollevels: male, young age, short diabetes duration, low body mass index, macrovascular complications, no microvascular

Keywords： type 2 diabetes     quality of care     macrovascular complication     microvascular complication     treatment pattern    

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Effect of current density on groundwater arsenite removal performance using air cathode electrocoagulation

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 6, doi: 10.1007/s11783-021-1399-1

Abstract:

• With the same charge, current density had little effect on As(III)

Keywords： Electrocoagulation     Air cathode     Arsenic     Current density     Energy consumption    

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Effects of exercise therapy on bone mineral density in early postmenopausal women: a controlled trial

Shilin DENG MD ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 323-329 doi: 10.1007/s11684-009-0061-2

Abstract: effect of a well-designed combined aerobic, resistance, and extension exercise program on bone mineral density

Keywords： early postmenopausal women     bone mineral density     exercise     effects    

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density measurement for plastic injection molding via ultrasonic technology

Frontiers of Mechanical Engineering 2022, Volume 17, Issue 4, doi: 10.1007/s11465-022-0714-2

Abstract: Density variation during the injection molding process directly reflects the state of plastic melt andTherefore, in-situ density measurement is of great interest and has significant application valueThis study is the first to propose an in-situ density measurement method using ultrasonic technology

Keywords： ultrasonic measurement     melt density     in-situ measurement     injection molding    

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Phytotoxicity in seven higher plant species exposed to di-

Tingting MA,Ying TENG,Peter CHRISTIE,Yongming LUO

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 2,   Pages 259-268 doi: 10.1007/s11783-014-0652-2

Abstract: We investigated phytotoxicity in seven plant species exposed to a range of concentrations (0– 500 mg·kg soil) of di- -butyl phthalate (DnBP) or bis (2-ethylhexyl) phthalate (DEHP), two representative phthalate esters (PAEs) nominated by USEPA as priority pollutants and known environmental estrogens. We studied seed germination, root elongation, seedling growth, biomass (fresh weight, FW) and malondialdehyde (MDA) content of shoots and roots of wheat ( L.), alfalfa ( L.), perennial ryegrass ( ), radish ( L.), cucumber ( L.), oat ( ) and onion ( L.), together with monitoring of plant pigment content (chlorophyll a, b and carotinoids) in alfalfa, radish and onion shoots. Root elongation, seedling growth and biomass of the test species were generally inhibited by DnBP but not by DEHP, indicating a lower level of phytotoxicity of DEHP than of DnBP. MDA contents of four species were promoted by PAE exposure, but not in alfalfa, ryegrass or onion shoots, indicating lower sensitivity of these three species to PAE pollutants. Plant pigment contents were clearly affected under the stress of both pollutants, implying the potential damage to the photosynthetic system of test plants, mainly by decreasing the content of chlorophyll a and b. Results of DnBP and DEHP phytotoxicity to the primary growth of test plants has provided information for the assessment of their environmental risk in the soil and also forms a basis for the further analysis of their toxic effects over the whole growth period of different plant species.

Keywords： phytotoxicity     di-n-butyl phthalate     bis(2-ethylhexyl) phthalate     malondialdehyde     plant pigments (chlorophyll a     b and carotinoids)    

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Isolating higher yielding and more stable rice genotypes in stress environments: fine-tuning a selection

Frontiers of Agricultural Science and Engineering doi: 10.15302/J-FASE-2023521

Abstract:

● Score index methods readily discriminate genotypes adapted to a target environment.

Keywords： Aerobic rice     breeding selection     drought resilience     production capacity index     resilience capacity index     stress score index     upland    

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Relationship of adrenomedullin expression and microvessel density and prognosis in smooth muscle tumor

JIANG Yuan, TIAN Xuehong, YUAN Jie, JIN Yuemei, TAN Yusong

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 398-400 doi: 10.1007/s11684-007-0077-4

Abstract: was to investigate the relationship between the expression of adrenomedullin (ADM) and microvessel densitycorrelation between the ADM expression and mitotic figures in LES (<0.05): the more mitotic figures, the higher

Keywords： anticarcinogenic     microvessel density     malignant potency     muscle     uterine leiomyosarcoma    

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Single-electromagnet levitation for density measurement and defect detection

Yuhan JIA, Peng ZHAO, Jun XIE, Xuechun ZHANG, Hongwei ZHOU, Jianzhong FU

Frontiers of Mechanical Engineering 2021, Volume 16, Issue 1,   Pages 186-195 doi: 10.1007/s11465-020-0608-0

Abstract: The single-electromagnet levitation device has a large measuring range and can realize accurate densitymeasurement and defect detection of high-density materials, such as glass and aluminum alloy.

Keywords： single-electromagnet     electromagnetic levitation     density measurement     defect detection    

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Application of gamma-ray attenuation technology in density measurement of a slurry reactor

Jian XU, Weisheng WEI, Kai ZHANG

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 4,   Pages 486-490 doi: 10.1007/s11705-010-0509-6

Abstract: Axial density profile of the gas-liquid-solid mixture in a slurry bubble column was measured by gamma-rayThe results showed that the density in the column decreases with the increase of column height, which

Keywords： slurry reactor     axial density distribution     gamma-ray attenuation technology    

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Title Author Date Type Operation

Lymphatic metastasis is related to the epithelial-mesenchymal transition and expressions of VEGF, MMP-9, and COX-2 in breast cancer

Lihui WANG, Lianhong LI, Shen LV, Shujun FAN, Li ZHAN, Bo WANG, Zhong ZHANG

Journal Article

FUNCTIONAL GAIN OF FRUIT NETTED-CRACKING IN AN INTROGRESSION LINE OF TOMATO WITH HIGHER EXPRESSION OF

Journal Article

Higher-order mode effects on the seismic performance of tall piers

Zhongguo GUAN, Jianzhong LI, Yan XU, Hao LU

Journal Article

Theoretical Study of Color Gamut of Higher Plant Leaves

Cheng Xiaofang,Dong Jinyi,Fan Xueliang,Ding Jinlei

Journal Article

Higher Moment Method in Reliability Analysis of Engineering Structure

Gong Fengqiang,Li Xibing,Deng Jian

Journal Article

Higher heating value prediction of torrefaction char produced from non-woody biomass

Nitipong SOPONPONGPIPAT,Dussadeeporn SITTIKUL,Unchana SAE-UENG

Journal Article

Effectiveness of quality of care for patients with type 2 diabetes in China: findings from the Shanghai Integration Model (SIM)

Journal Article

Effect of current density on groundwater arsenite removal performance using air cathode electrocoagulation

Journal Article

Effects of exercise therapy on bone mineral density in early postmenopausal women: a controlled trial

Shilin DENG MD ,

Journal Article

density measurement for plastic injection molding via ultrasonic technology

Journal Article

Phytotoxicity in seven higher plant species exposed to di-

Tingting MA,Ying TENG,Peter CHRISTIE,Yongming LUO

Journal Article

Isolating higher yielding and more stable rice genotypes in stress environments: fine-tuning a selection

Journal Article

Relationship of adrenomedullin expression and microvessel density and prognosis in smooth muscle tumor

JIANG Yuan, TIAN Xuehong, YUAN Jie, JIN Yuemei, TAN Yusong

Journal Article

Single-electromagnet levitation for density measurement and defect detection

Yuhan JIA, Peng ZHAO, Jun XIE, Xuechun ZHANG, Hongwei ZHOU, Jianzhong FU

Journal Article

Application of gamma-ray attenuation technology in density measurement of a slurry reactor

Jian XU, Weisheng WEI, Kai ZHANG

Journal Article